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SS-31 is a synthetic tetrapeptide (4 amino acids long) designed as a mitochondria-targeting aromatic-cationic peptide, incorporating D-arginine at the N-terminus, 2,6-dimethyltyrosine (Dmt or 2,6-diMe-Tyr) as a modified aromatic residue, lysine, and phenylalanine with C-terminal amidation for enhanced stability and membrane permeability.
Store in a cool, dark place or freeze at -20°C for long term storage. Refrigerate after reconstitution
Product Name: SS-31
CAS: 736992-21-5
Molecular Mass: 639.8 g/mol
Molecular Formula: C32H49N9O5
PubChem ID: 11764719
SS-31 is a synthetic tetrapeptide (4 amino acids long) designed as a mitochondria-targeting aromatic-cationic peptide, incorporating D-arginine at the N-terminus, 2,6-dimethyltyrosine (Dmt or 2,6-diMe-Tyr) as a modified aromatic residue, lysine, and phenylalanine with C-terminal amidation for enhanced stability and membrane permeability.
Its amino acid sequence is: D-Arg-Dmt-Lys-Phe-NH₂ (or H-D-Arg-(2,6-dimethyl)Tyr-Lys-Phe-NH₂, with the D-configuration at Arg and C-terminal amidation).
Chemically, it has the molecular formula C₃₂H₄₉N₉O₅ and a molar mass of approximately 639.8 g/mol (CAS 736992-21-5 for the free base). This oligopeptide is classified as a research chemical and is commonly utilized in laboratory investigations of mitochondrial biochemistry, peptide-membrane interactions, and related cellular pathways
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