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Semax is a synthetic heptapeptide with nootropic and neuroprotective properties, mimicking ACTH 4-10, that enhances cognitive function and neuronal survival by modulating BDNF, NGF, and monoaminergic systems, primarily used in Russia for conditions like stroke and cognitive impairment.1.6sFast
Store in a cool, dark place or freeze at -20°C for long term storage. Refrigerate after reconstitution
Product Name: Semax
CAS:80714-61-0
Molecular Mass:
813.92 g/mol
Molecular Formula:
C₃₇H₅₁N₉O₁₀S
Semax is a synthetic heptapeptide, structurally analogous to adrenocorticotropic hormone (ACTH) fragment 4-10, with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. Developed in Russia, it is primarily investigated for its nootropic, neuroprotective, and neuroregenerative properties. Semax acts by modulating the expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), enhancing synaptic plasticity and neuronal survival. It also exhibits immunomodulatory effects and influences the dopaminergic and serotoninergic systems, potentially improving cognitive function, memory, and stress resilience. Administered intranasally or subcutaneously, Semax rapidly crosses the blood-brain barrier, with studies suggesting efficacy in treating conditions like stroke, traumatic brain injury, and cognitive impairment, though its mechanisms are not fully elucidated and clinical data remain limited outside Russia.
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