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Thymosin Alpha 1 (Tα1) is a synthetic 28-amino acid peptide derived from prothymosin alpha that is researched for its immunomodulatory effects on T-cell maturation, NK and dendritic cell function, and production of key cytokines such as IL-2 and IFN-γ.
Product Name: Thymosin Alpha 1
CAS Number:62304-98-7
Molecular Formula:C₁₂₉H₂₁₅N₃₃O₅₅
Molecular Mass (Weight):3108.3 g/mol
PubChem ID (CID):16130571
Thymosin Alpha 1 (Tα1) is a synthetic 28-amino acid peptide that corresponds to the N-terminal region of the naturally occurring protein prothymosin alpha. First isolated from thymic tissue, it has become a well-characterized immunomodulatory compound extensively studied for its effects on both innate and adaptive immunity. In research models, Thymosin Alpha 1 has been shown to promote the differentiation and maturation of T-lymphocytes, enhance the function of natural killer (NK) cells and dendritic cells, and stimulate the production of key cytokines including interleukin-2 (IL-2), interferon-gamma (IFN-γ), and other Th1-associated signaling molecules. These actions contribute to improved antigen presentation, strengthened cell-mediated immune responses, and restoration of immune balance in states of immunodeficiency or immune dysregulation.
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