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MOTS-c (also known as mitochondrial open reading frame of the 12S rRNA-c or MOTS3) is a synthetic hexadecapeptide (16 amino acids long) derived from a short open reading frame encoded within the mitochondrial 12S rRNA gene (MT-RNR1), representing a mitochondrial-derived peptide (MDP) that is chemically synthesized for research purposes without glycosylation or other post-translational modifications in its standard form.
Product Name: MOTS-C
CAS: 1627580-64-6
Molecular Mass: 2174.6 g/mol
Molecular Formula: C101H152N28O22S2
PubChem ID: 146675088
MOTS-c (also known as mitochondrial open reading frame of the 12S rRNA-c or MOTS3) is a synthetic hexadecapeptide (16 amino acids long) derived from a short open reading frame encoded within the mitochondrial 12S rRNA gene (MT-RNR1), representing a mitochondrial-derived peptide (MDP) that is chemically synthesized for research purposes without glycosylation or other post-translational modifications in its standard form.
Its amino acid sequence is: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (or H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH, with free N- and C-termini).
Chemically, it has the molecular formula C₁₀₁H₁₅₂N₂₈O₂₂S₂ and a molar mass of approximately 2174.6–2174.64 g/mol (CAS 1627580-64-6). This oligopeptide is classified as a research chemical and is commonly utilized in laboratory investigations of mitochondrial-encoded peptide biochemistry, metabolic pathways, and related cellular processes
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